Assessment of the cornea during a keratoconus examination

Keratoconus
& Treatment

Early diagnosis and modern treatments that halt the disease in which the cornea thins and bulges into a cone, distorting vision.

About Keratoconus

Keratoconus is a progressive corneal disorder in which the cornea — the transparent front layer of the eye — gradually thins and bulges forward into a cone shape. It usually begins in adolescence or young adulthood and, if untreated, can seriously degrade visual quality.

Its course varies from person to person; in some it progresses slowly, in others it worsens rapidly. Early diagnosis and regular follow-up are therefore crucial to halt progression in time and protect vision.

What Is Keratoconus?

A healthy cornea has a balanced, dome-shaped structure that refracts light evenly to form a sharp image on the retina. In keratoconus the corneal tissue weakens and, under the eye’s internal pressure, bulges forward into a cone. This irregularity causes light to refract unevenly and produces an astigmatism that is difficult to correct.

The disease usually affects both eyes but is generally more pronounced in one. As it progresses, glasses and standard lenses may no longer give adequate vision. For treatments that preserve the structural strength of the cornea, an assessment for corneal cross-linking and other corneal conditions is also made.

Symptoms

Keratoconus can be silent early on; as it progresses the following become apparent:

  • Frequently changing prescription: Prescriptions that increase at short intervals and never quite settle.
  • Progressive astigmatism: Blur that becomes increasingly hard to correct with standard lenses.
  • Glare and halos at night: Halos, streaking and flare around headlights and lamps.
  • Blurred and ghosted vision: Double vision in one eye or shadowing of letters.
  • Contact lens intolerance: Lenses that no longer sit properly and become uncomfortable.

Causes & Risk Factors

The exact cause of keratoconus is not fully known, but several factors play a role:

  • Genetic predisposition: Risk is higher in people with a family history of keratoconus.
  • Persistent eye rubbing: Vigorous rubbing, especially due to allergy, mechanically weakens the cornea.
  • Allergic eye disease: Chronic allergy and eye itching can trigger the disease.
  • Young age: It usually begins in adolescence and tends to progress.
  • Certain systemic conditions: It may be associated with some connective-tissue and genetic syndromes.

Avoiding eye rubbing and keeping allergy under control are simple but effective measures to slow progression.

Diagnosis

Early diagnosis is critical so progression-halting treatments can be applied in time. Assessment uses:

  • Corneal topography: Maps the corneal surface to reveal the earliest changes.
  • Corneal tomography (e.g. Pentacam): Measures the front and back surfaces and thickness of the cornea in detail.
  • Pachymetry: Measures corneal thickness to grade the degree of thinning.
  • Slit-lamp examination: Thinning, striae and other signs are examined under magnification.
  • Refraction follow-up: The speed of prescription change is an important indicator of progression.

Treatment

Halting Progression

Cross-Linking

Corneal cross-linking icon

The key treatment in progressive keratoconus, strengthening the cornea to halt the disease.

1
Applying riboflavin

Riboflavin

Vitamin B2 (riboflavin) is applied to prepare the corneal tissue.

2
UV light application

UV Light

Controlled ultraviolet light creates new bonds between the corneal fibres.

3
Bandage lens

Healing

A bandage lens protects the surface afterwards and supports healing.

Progression Halted

Improving Vision

Lenses & Rings

Contact lens icon

Lens and intracorneal-ring options that compensate for the shape distortion to deliver clear vision.

1
Specialty lens fitting

Rigid / Scleral Lens

Rigid gas-permeable or scleral lenses compensate for the irregular surface.

2
Intracorneal ring

Corneal Ring

Ring segments placed within the cornea flatten the cone.

3
Advanced-case assessment

Corneal Transplant

In very advanced cases a corneal transplant restores vision.

Clear, Comfortable Vision

Is your keratoconus progressing?

Based on topography and tomography findings, the most suitable treatment plan is decided together.

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Frequently Asked Questions

Keratoconus does not usually lead to total blindness, but if untreated it can seriously reduce visual quality. With early diagnosis and treatments such as cross-linking, progression can largely be halted and vision preserved.
The main aim of cross-linking is not to correct vision but to strengthen the cornea and halt progression. Visual acuity is improved with glasses, specialty lenses or intracorneal rings.
In early stages glasses or soft lenses may give adequate vision. As the disease progresses, the irregular astigmatism often requires rigid gas-permeable or scleral lenses.
Yes. Constant, hard eye rubbing mechanically stresses the cornea and can trigger keratoconus or speed its progression. Avoiding eye rubbing is especially important for people with allergies.