Fundus image during retinal examination

Retinal
Diseases

A comprehensive approach for early diagnosis and treatment of all vision-threatening conditions, from retinal tears to diabetic retinopathy.

About Retinal Diseases

The retina is the light-sensitive layer lining the back of the eye and is responsible for transmitting images to the brain. Trauma, genetic factors, metabolic diseases, or environmental conditions can affect the retina and rapidly reduce visual quality.

Inherited conditions such as Stargardt disease, age-related degeneration, systemic disorders like diabetes and hypertension, or direct retinal tears may cause permanent damage in this layer. Early diagnosis is critical for preserving retinal function.

What Is the Retina?

The retina is a thin layer where light is converted into electrical signals and transmitted to the brain through the optic nerve. When the retina is damaged, the signals reaching the brain are disrupted; therefore, even small changes can create spots, distortions, and dark areas in the visual field.

How Do Retinal Diseases Develop?

The main mechanisms that affect the retina include:

  • Genetic predisposition: Inherited diseases such as Stargardt disease or retinitis pigmentosa gradually damage photoreceptor cells.
  • Metabolic disorders: Diabetes and hypertension weaken capillary walls, leading to fluid leakage into the retina.
  • Aging: Degeneration develops in the macula, impairing central vision.
  • Trauma and surgery: Vitreous shrinkage or head trauma increases the risk of retinal tears and detachment.
  • Infection and inflammation: May cause edema and scarring in the retinal layer, leading to lasting impairment.

Symptoms and Warning Signs

Recognizing early symptoms of retinal disease helps prevent vision loss:

  • Floaters and flashes: May indicate a retinal tear or vitreous detachment.
  • Blurred or distorted vision: Suggests macular disease.
  • Marked decrease in night vision: A typical sign of retinitis pigmentosa.
  • Shadows in the visual field: As retinal detachment progresses, a curtain-like shadow may appear.
  • Eye pain and redness: May accompany diabetic retinopathy or inflammatory processes.

Common Retinal Diseases

Retinal Tear

As the vitreous gel liquefies and shrinks, it may separate from the retina. Sudden floaters and flashes can indicate this condition. If the tear is not sealed with laser promptly, it can progress to detachment.

Retinal Detachment

When fluid accumulates under the retina, the layer separates from the underlying tissues. If untreated, permanent blindness may occur; urgent intervention is performed with vitrectomy, tamponade, and laser combinations.

Diabetic Retinopathy

High blood sugar weakens capillaries, causing fluid leakage and swelling in the retina. Blurred vision, pain, redness, and sudden vision loss may occur; regular screening is essential.

Macular Hole

A hole forming in the center of the macula may create a dark spot in the visual field. Aging and trauma are common causes; treatment includes vitrectomy and gas tamponade.

Macular Degeneration

Known as “yellow spot” disease, this condition blurs central vision as the macula deteriorates. In age-related forms, anti-VEGF injections and lifestyle changes are important.

Retinitis Pigmentosa

In this genetic disease, often associated with night blindness, the visual field gradually narrows. It is progressive; early rehabilitation and genetic counseling can improve quality of life.

Diagnostic and Treatment Approach

Advanced imaging techniques such as optical coherence tomography (OCT), fundus photography, and fluorescein angiography enable detailed evaluation of retinal layers. Laser photocoagulation is used for tears, vitrectomy for detachment, and anti-VEGF injections or membrane peeling for macular diseases.

In diabetic retinopathy, metabolic control, anti-VEGF therapies, and vitreoretinal surgery are combined when needed. Each case requires a personalized treatment plan based on the type of retinal involvement.

Frequently Asked Questions

Floaters, flashes of light, distorted or blurred vision, reduced night vision, and sudden vision loss are among the earliest signals of retinal disease.
As detachment progresses, the retina cannot be nourished and permanent vision loss may occur. Laser or surgical intervention is needed before fluid accumulates under the retina.
In diabetic retinopathy, capillaries are damaged and fluid leaks into and under the retina. Vision may become blurred, with possible pain and redness; regular check-ups are essential.