Eye examination for uveitis (intraocular inflammation)

Uveitis
& Treatment

Inflammation of the eye’s middle layer; early diagnosis and treatment prevent permanent vision loss.

About Uveitis

Uveitis is inflammation of the uvea, the middle layer of the eye. It may be linked to infections, rheumatic diseases or immune-system problems, and sometimes no cause is found.

Because untreated uveitis can lead to permanent vision loss through complications such as cataract, glaucoma and macular oedema, early diagnosis and treatment are very important.

What Is Uveitis?

The uvea contains many of the eye’s blood vessels, so when it becomes inflamed the whole eye can be affected. Uveitis is classified by location — anterior (front), intermediate, posterior (back) or involving the whole eye.

It can be a one-off episode or recur over time, especially when linked to an immune or rheumatic condition. Identifying any underlying cause is a key part of treatment.

Symptoms

Uveitis can begin suddenly or gradually; common signs are:

  • Eye pain: A deep ache, especially in anterior uveitis.
  • Redness: Persistent redness, often around the coloured part of the eye.
  • Light sensitivity: Discomfort in bright light (photophobia).
  • Blurred vision: Reduced clarity as inflammation affects the eye.
  • Floaters: Dark spots drifting across vision in posterior types.

Causes & Risk Factors

Uveitis has many possible triggers:

  • Autoimmune / rheumatic disease: Conditions such as ankylosing spondylitis and Behçet’s disease.
  • Infections: Viral, bacterial, fungal or parasitic infections.
  • Trauma: Injury to the eye can provoke inflammation.
  • Systemic inflammatory disease: Sarcoidosis and similar conditions.
  • Idiopathic: In many cases no specific cause is identified.

Diagnosis

Diagnosis combines eye examination with a search for underlying causes:

  • Slit-lamp examination: Detects inflammatory cells in the eye.
  • Dilated fundus examination: Assesses the retina and posterior segment.
  • OCT: Detects macular oedema and monitors response.
  • Blood tests / imaging: Search for an associated systemic disease.
  • Pressure check: Screens for secondary glaucoma.

Treatment

Controlling Inflammation

Medical Therapy

Medication icon

Treatment suppresses inflammation quickly to relieve symptoms and protect the eye.

1
Steroid drops

Steroids

Topical or systemic steroids reduce active inflammation.

2
Pupil-dilating drops

Comfort

Dilating drops ease pain and prevent adhesions.

3
Follow-up

Follow-up

Response is monitored and treatment tapered carefully.

Inflammation Controlled

Resistant / Recurrent

Advanced Therapy

Advanced therapy icon

In recurrent or severe cases, treatment targets the underlying immune process.

1
Immunosuppressants

Immunomodulation

Steroid-sparing agents control chronic inflammation.

2
Biologic agents

Biologics

Targeted biologics are used in selected resistant cases.

3
Treating the cause

Underlying Cause

Any infection or systemic disease is treated alongside.

Long-term Control

Do you have eye pain, redness and light sensitivity?

Prompt assessment controls inflammation and reduces the risk of complications.

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Frequently Asked Questions

Uveitis, especially when linked to rheumatic or immune conditions, tends to recur. After flare-ups are controlled, regular follow-up and management of the underlying disease are important; early treatment reduces the risk of permanent damage from attacks.
Untreated or delayed uveitis can cause complications such as cataract, glaucoma and macular oedema and lead to permanent loss. With early diagnosis and regular treatment, vision is preserved in most patients.
Uveitis itself is not contagious. When it is caused by an infection, the underlying infection is treated; most cases are linked to immune or rheumatic conditions rather than transmission.
It varies with the type and cause. A single episode may settle in weeks, while recurrent or chronic uveitis may need long-term treatment and monitoring to keep inflammation under control.